Betthauser Laboratory

The Betthauser Lab conducts aging and dementia research focused on using neuroimaging, fluid biomarkers, and neuropathology to better understand the earliest detectable changes in neurodegenerative disease such as Alzheimer’s disease.

Our lab specifically uses a multidisciplinary approach that combines neuropathology, quantitative imaging and fluid biomarkers, and clinical data to better understand the timing of Alzheimer’s disease pathology and how this interacts with other brain pathologies to impact clinical progression.

We develop and apply novel longitudinal image processing and modeling methods to better understand the sequence and timing of biomarker detectable events in neurodegenerative disease and whether these temporal variables are consequential for downstream cognitive dysfunction and impairment.

We are a part of the larger Wisconsin Alzheimer’s Disease Research Program at the University of Wisconsin-Madison, which includes both the Wisconsin Alzheimer’s Disease Research Center and the Wisconsin Alzheimer’s Institute. We also work in close collaboration with the Center for Health Disparities Research (CHDR).